When I was diagnosed with acute myeloid leukemia, I was informed I had a gene mutation. How do genetic mutations and chromosomal abnormalities form and how are they able to go back to normal after chemotherapy? Was this gene mutation caused by something I did? - by Elissa B from USA Topics: acute myeloid leukemia, BRCA2, chemotherapy, chromosomal abnormalities', DDX41 (Dead-Box Helicase 41), DNA, DNA repair genes, GATA2, genetic clock, genetic risk, Genetics, hematological malignancies, inversion 16, molecular, tumor suppressor genes View Answer