I'd like to know what causes TKI withdrawal syndrome and why do some people get it so much worse than others. - by Tracey F from USA Topics: anti-inflammatories, antihistamines, arthritic symptoms, BCR-ABL, chronic myeloid leukemia (CML), fatigue, inflammatory symptoms, joint pain, KIT, mechanical symptoms, TKI therapy, TKI withdrawal syndrome, treatment free remission (TFR), tyrosine kinase inhibitors (TKI), withdrawal syndrome View Answer